Primary studyYeast & synthetic biology
Construction and iterative redesign of synXVI a 903 kb synthetic Saccharomyces cerevisiae chromosome
Builds synthetic yeast chromosome XVI and documents design defects and repairs.
2025
Research field / 02
Yeast & synthetic biology
What can a living cell carry?
Humanized yeast and synthetic chromosomes show that cells can be engineered to carry selected sequences and perform specific functions. These studies give the Culture a research context. They do not demonstrate the proposed memorial product, complete body conversion or the preservation of a person.
Questions that matter
- What would a signature sequence represent, and how would consent cover its use?
- Can the proposed culture maintain identity, viability and genetic stability over time?
- What independent evidence would establish performance and containment?
Sources & resources
Read our evidence note, then follow the original source.
PerspectiveYeast & synthetic biology
Towards the construction of a virtual yeast
Proposes an AI-driven virtual yeast linking biological data, models and experiments.
2026
Primary studyYeast & synthetic biology
Systematic humanization of yeast genes reveals conserved functions and genetic modularity
Tests human genes as replacements for essential yeast genes.
2015
Humanized yeast to model human biology, disease and evolution
Reviews humanized yeast models of human gene function and disease variants.
2022
Primary studyYeast & synthetic biology
The adaptive molecular landscape of reprogrammed telomeric sequences
Examines molecular adaptation to human-like telomeric repeats in yeast.
2026
DatabaseYeast & synthetic biology
Saccharomyces Genome Database
Curated yeast genes, pathways, literature and analysis tools.
Resource
Primary studyYeast & synthetic biology
Iterative SCRaMbLE for engineering synthetic genome modules and chromosomes
Investigates iterative rearrangement of synthetic genome modules and chromosomes.
2025
Primary studyYeast & synthetic biology
Debugging and consolidating multiple synthetic chromosomes reveals combinatorial genetic interactions
Combines synthetic chromosomes and investigates interacting design defects.
2023
CommentaryYeast & synthetic biology
Building synthetic chromosomes one yeast at a time: insights from Sc2.0
Sc2.0 researchers reflect on synthetic yeast chromosome construction.
2025