Construction and iterative redesign of synXVI a 903 kb synthetic Saccharomyces cerevisiae chromosome
Builds synthetic yeast chromosome XVI and documents design defects and repairs.
Proposes an AI-driven virtual yeast linking biological data, models and experiments.
A research agenda, not a validated whole-cell simulation.
Humanized yeast and synthetic chromosomes show that cells can be engineered to carry selected sequences and perform specific functions. These studies give the Culture a research context. They do not demonstrate the proposed memorial product, complete body conversion or the preservation of a person.
Builds synthetic yeast chromosome XVI and documents design defects and repairs.
Tests human genes as replacements for essential yeast genes.
Reviews humanized yeast models of human gene function and disease variants.