Iterative SCRaMbLE for engineering synthetic genome modules and chromosomes

Nature Portfolio · 2025 · Indexed 8 October 2026

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What this contributes

Investigates iterative rearrangement of synthetic genome modules and chromosomes.

The boundary of the evidence

Genome engineering introduces stability and fitness tradeoffs.

Why it belongs here

Humanized yeast and synthetic chromosomes show that cells can be engineered to carry selected sequences and perform specific functions. These studies give the Culture a research context. They do not demonstrate the proposed memorial product, complete body conversion or the preservation of a person.

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