RegulationContainment & biosafety
TSCA Biotechnology Regulations
EPA explains TSCA review for certain new microorganisms.
Resource
ReviewContainment & biosafety
Advances in biocontainment strategies of engineered microbes for use in humans
What this contributes
Surveys containment approaches for engineered microbes used in humans.
The boundary of the evidence
Strategies require organism-specific validation.
Why it belongs here
A culture kept in a vessel and one released into soil present different questions. Physical and biological containment, strain stability and institutional oversight must be assessed for the actual organism and use. A laboratory finding is not an environmental release authorization.
Keep reading
GuidanceContainment & biosafety
Biosafety in Microbiological and Biomedical Laboratories (BMBL) 6th Edition
CDC and NIH's sixth-edition BMBL emphasizes risk assessment and containment.
2020
GuidanceContainment & biosafety
4.1.27 Research Involving Recombinant or Synthetic Nucleic Acid Molecules (including Human Gene Transfer Research)
NIH explains applicability of recombinant and synthetic nucleic-acid guidelines.
2026