RegulationContainment & biosafety
TSCA Biotechnology Regulations
EPA explains TSCA review for certain new microorganisms.
Resource
ReviewContainment & biosafety
Design and regulation of engineered bacteria for environmental release
What this contributes
Reviews engineering and regulation of microbes intended for environmental release.
The boundary of the evidence
Laboratory performance does not establish environmental safety.
Why it belongs here
A culture kept in a vessel and one released into soil present different questions. Physical and biological containment, strain stability and institutional oversight must be assessed for the actual organism and use. A laboratory finding is not an environmental release authorization.
Keep reading
GuidanceContainment & biosafety
Biosafety in Microbiological and Biomedical Laboratories (BMBL) 6th Edition
CDC and NIH's sixth-edition BMBL emphasizes risk assessment and containment.
2020
GuidanceContainment & biosafety
4.1.27 Research Involving Recombinant or Synthetic Nucleic Acid Molecules (including Human Gene Transfer Research)
NIH explains applicability of recombinant and synthetic nucleic-acid guidelines.
2026